SP1‐mediated upregulation of LINGO‐1 promotes degeneration of retinal ganglion cells in optic nerve injury

BACKGROUNDS: Insults to the axons in the optic nerve head are the primary cause of loss of retinal ganglion cells (RGCs) in traumatic, ischemic nerve injury or degenerative ocular diseases. The central nervous system–specific leucine‐rich repeat protein, LINGO‐1, negatively regulates axon regenerati...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Wu, Yali, Zhan, Zongyi, Quan, Yadan, Yang, Yangfan, Chen, Xiaotao, Liu, Liling, Wu, Kaili, Yu, Minbin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539844/
https://ncbi.nlm.nih.gov/pubmed/32562344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13426
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