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Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons

PURPOSE. This study investigated the role of sterile alpha/Armadillo/Toll-Interleukin receptor homology domain 1 protein (SARM1) in Wallerian-like degeneration of retinal ganglion cells (RGCs) and their axons after inducing excitotoxicity. METHODS. To induce excitotoxicity, kainic acid (KA) was inje...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Massoll, Charlotte, Mando, Wasym, Chintala, Shravan K.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Association for Research in Vision and Ophthalmology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632266/
https://ncbi.nlm.nih.gov/pubmed/23518770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10973
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