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Activation of TLR3 Promotes the Degeneration of Retinal Ganglion Cells by Upregulating the Protein Levels of JNK3

PURPOSE. To investigate whether activation of Toll-like receptor 3 (TLR3) promotes the degeneration of retinal ganglion cells (RGCs) by upregulating the protein levels of c-jun N-terminal kinase 3 (JNK3). METHODS. Toll-like receptor 3-specific activator, Poly(I:C) (polyinosinic-polycytidylic acid),...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Chintala, Shravan K., Putris, Nahrain, Geno, Mason
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299467/
https://ncbi.nlm.nih.gov/pubmed/25564448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15539
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