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A decrease in phosphorylation of cAMP-response element-binding protein (CREBP) promotes retinal degeneration

Excitotoxicity, induced either by N-Methyl-D-aspartate (NMDA) or kainic acid (KA), promotes irreversible loss of retinal ganglion cells (RGCs). Although the intracellular signaling mechanisms underlying excitotoxic cell death are still unclear, recent studies on the retina indicate that NMDA promote...

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Detalhes bibliográficos
Main Authors: Mali, Raghuveer S, Zhang, Xiao M, Chintala, Shravan K
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104104/
https://ncbi.nlm.nih.gov/pubmed/21459086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2011.03.017
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