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A decrease in phosphorylation of cAMP-response element-binding protein (CREBP) promotes retinal degeneration

Excitotoxicity, induced either by N-Methyl-D-aspartate (NMDA) or kainic acid (KA), promotes irreversible loss of retinal ganglion cells (RGCs). Although the intracellular signaling mechanisms underlying excitotoxic cell death are still unclear, recent studies on the retina indicate that NMDA promote...

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Hlavní autoři: Mali, Raghuveer S, Zhang, Xiao M, Chintala, Shravan K
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104104/
https://ncbi.nlm.nih.gov/pubmed/21459086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2011.03.017
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