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Allopregnanolone restores the tyrosine hydroxylase‐positive neurons and motor performance in a 6‐OHDA‐injected mouse model

AIMS: It has been reported that allopregnanolone (APα) promotes the neurogenesis of the neural progenitor cells (NPCs) in the subventricular zone (SVZ) and prevents the decrease of dopaminergic neurons in 6‐hydroxydopamine (6‐OHDA)‐treated mice by binding to γ‐aminobutyric acid A receptor (GABAAR) a...

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Dettagli Bibliografici
Pubblicato in:CNS Neurosci Ther
Autori principali: Chen, Zhi‐Chi, Wang, Tong‐Tong, Bian, Wei, Ye, Xin, Li, Meng‐Yi, Du, Juan‐Juan, Zhou, Peng, Cui, Huai‐Rui, Ding, Yu‐Qiang, Ren, Yan‐hua, Qi, Shuang‐Shuang, Yuan, Yuan‐Yuan, Liao, Min, Sun, Chen‐You
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539840/
https://ncbi.nlm.nih.gov/pubmed/32602622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13432
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