Ceftriaxone increases glutamate uptake and reduces striatal tyrosine hydroxylase loss in 6-OHDA Parkinson’s model

Excess glutamatergic neurotransmission may contribute to excitotoxic loss of nigrostriatal neurons in Parkinson’s disease (PD). Here, we determined if increasing glutamate uptake could reduce the extent of tyrosine hydroxylase (TH) loss in PD progression. The beta-lactam antibiotic, ceftriaxone, inc...

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Bibliografiset tiedot
Julkaisussa:Mol Neurobiol
Päätekijät: Chotibut, Tanya, Davis, Richard W., Arnold, Jennifer C., Frenchek, Zachary, Gurwara, Shawn, Bondada, Vimala, Geddes, James W., Salvatore, Michael F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618839/
https://ncbi.nlm.nih.gov/pubmed/24297323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-013-8598-0
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