Using 10,000 Fragment Ions to Inform Scoring in Native Top-down Proteomics

Protein fragmentation is a critical component of top-down proteomics, enabling gene-specific protein identification and full proteoform characterization. The factors that influence protein fragmentation include precursor charge, structure, and primary sequence, which have been explored extensively f...

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Vydáno v:J Am Soc Mass Spectrom
Hlavní autoři: Ives, Ashley N., Su, Taojunfeng, Durbin, Kenneth R., Early, Bryan P., dos Santos Seckler, Henrique, Fellers, Ryan T., LeDuc, Richard D., Schachner, Luis F., Patrie, Steven M., Kelleher, Neil L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539637/
https://ncbi.nlm.nih.gov/pubmed/32436704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jasms.0c00026
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