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Anethole Dithiolethione Increases Glutathione in Kidney by Inhibiting γ-Glutamyltranspeptidase: Biochemical Interpretation and Pharmacological Consequences

AIMS: Anethole dithiolethione (ADT) is a marketed drug to treat xerostomia. Its mechanism of action is still unknown, but several preclinical studies indicate that it is able to increase intracellular glutathione (GSH) and protect against oxidative stress. Here, we investigated the molecular mechani...

詳細記述

保存先:
書誌詳細
出版年:Oxid Med Cell Longev
主要な著者: Giustarini, Daniela, Galvagni, Federico, Dalle-Donne, Isabella, Milzani, Aldo, Lucattelli, Monica, De Cunto, Giovanna, Bartolini, Desirée, Galli, Francesco, Santucci, Annalisa, Rossi, Ranieri
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539083/
https://ncbi.nlm.nih.gov/pubmed/33062138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3562972
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