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Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions

The neurodegenerative Alzheimer’s disease (AD) affects more than 30 million people worldwide. There is thus far no cure or prevention for AD. Aggregation of hyperphosphorylated tau in the brain correlates with the cognitive decline of patients of AD and other neurodegenerative tauopathies. Intracere...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Liu, Mengyu, Dexheimer, Thomas, Sui, Dexin, Hovde, Stacy, Deng, Xiexiong, Kwok, Roland, Bochar, Daniel A., Kuo, Min-Hao
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539012/
https://ncbi.nlm.nih.gov/pubmed/33024171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73680-2
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