Hyperphosphorylation Renders Tau Prone to Aggregate and to Cause Cell Death

Alzheimer’s disease (AD) is a neurodegenerative disorder without a cure or prevention to date. Hyperphosphorylated tau forms the neurofibrillary tangles (NFTs) that correlate well with the progression of cognitive impairments. Animal studies demonstrated the pathogenic role of hyperphosphorylated ta...

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Publicat a:Mol Neurobiol
Autors principals: Liu, Mengyu, Sui, Dexin, Dexheimer, Thomas, Hovde, Stacy, Deng, Xiexiong, Wang, Kuang-Wei, Lin, Hsin Lian, Chien, Hsiao-Tien, Kweon, Hye Kyong, Kuo, Nora Sheen, Ayoub, Christopher A., Jimenez-Harrison, Daniela, Andrews, Philip C., Kwok, Roland, Bochar, Daniel A, Kuret, Jeff, Fortin, Jessica, Tsay, Yeou-Guang, Kuo, Min-Hao
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530023/
https://ncbi.nlm.nih.gov/pubmed/32780352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-02034-w
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