Protein Interaction Module–assisted Function X (PIMAX) Approach to Producing Challenging Proteins Including Hyperphosphorylated Tau and Active CDK5/p25 Kinase Complex

Many biomedically critical proteins are underrepresented in proteomics and biochemical studies because of the difficulty of their production in Escherichia coli. These proteins might possess posttranslational modifications vital to their functions, tend to misfold and be partitioned into bacterial i...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Sui, Dexin, Xu, Xinjing, Ye, Xuemei, Liu, Mengyu, Mianecki, Maxwell, Rattanasinchai, Chotirat, Buehl, Christopher, Deng, Xiexiong, Kuo, Min-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Technological Innovation and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288260/
https://ncbi.nlm.nih.gov/pubmed/25385071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O114.044412
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