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LncRNA-BLACAT1 Facilitates Proliferation, Migration and Aerobic Glycolysis of Pancreatic Cancer Cells by Repressing CDKN1C via EZH2-Induced H3K27me3
OBJECTIVE: To investigate the role of lncRNA-BLACAT1 in promoting H3K27 trimethylation of CDKN1C gene by recruiting EZH2 to regulate CCNE on glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer (PC) cells. METHODS: Following bioinformatic prediction, EZH2 and BLACAT1 in PC cel...
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| Publicat a: | Front Oncol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7538708/ https://ncbi.nlm.nih.gov/pubmed/33072570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.539805 |
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