Diagnostic Test Criteria for HLA Genotyping to Prevent Drug Hypersensitivity Reactions: A Systematic Review of Actionable HLA Recommendations in CPIC and DPWG Guidelines

INTRODUCTION: Certain HLA variants are associated with an increased risk of hypersensitivity reactions to specific drugs. Both the Clinical Pharmacogenetics Implementation Consortium (CPIC) and the Dutch Pharmacogenetics Working Group (DPWG) have issued actionable HLA gene – drug interaction guideli...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Manson, Lisanne E. N., Swen, Jesse J., Guchelaar, Henk-Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538700/
https://ncbi.nlm.nih.gov/pubmed/33071783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.567048
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