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HIF-2α is indispensable for regulatory T cell function
Hypoxia-inducible factor 1α (HIF-1α) and HIF-2α are master transcription factors that regulate cellular responses to hypoxia, but the exact function in regulatory T (Treg) cells is controversial. Here, we show that Treg cell development is normal in mice with Foxp3-specific knockout (KO) of HIF-1α o...
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| Yayımlandı: | Nat Commun |
|---|---|
| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7538433/ https://ncbi.nlm.nih.gov/pubmed/33024109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18731-y |
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