Recombinant human heterodimeric IL-15 complex displays extensive and reproducible N- and O-linked glycosylation

Human interleukin 15 (IL-15) circulates in blood as a stable molecular complex with the soluble IL-15 receptor alpha (sIL-15Rα). This heterodimeric IL-15:sIL-15Rα complex (hetIL-15) shows therapeutic potential by promoting the growth, mobilization and activation of lymphocytes and is currently evalu...

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Publicat a:Glycoconj J
Autors principals: Thaysen-Andersen, M., Chertova, E., Bergamaschi, C., Moh, E. S. X., Chertov, O., Roser, J., Sowder, R., Bear, J., Lifson, J., Packer, N. H., Felber, B. K., Pavlakis, G. N.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537637/
https://ncbi.nlm.nih.gov/pubmed/26563299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-015-9627-1
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