Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome

In response to T cell–dependent antigens, mature B cells are stimulated to form germinal centers (GCs), the sites of B cell affinity maturation and the cell of origin (COO) of most B cell lymphomas. To explore the dynamics of GC B cell development beyond the known dark zone and light zone compartmen...

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Bibliografski detalji
Izdano u:J Exp Med
Glavni autori: Holmes, Antony B., Corinaldesi, Clarissa, Shen, Qiong, Kumar, Rahul, Compagno, Nicolo, Wang, Zhong, Nitzan, Mor, Grunstein, Eli, Pasqualucci, Laura, Dalla-Favera, Riccardo, Basso, Katia
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537389/
https://ncbi.nlm.nih.gov/pubmed/32603407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200483
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