Activation of Wnt signaling promotes olaparib resistant ovarian cancer

Epithelial ovarian cancer (EOC) has one of the highest deaths to incidence ratios among all cancers. High grade serous ovarian carcinoma (HGSOC) is the most common and deadliest EOC histotype due to the lack of therapeutic options following debulking surgery and platinum/taxane-based chemotherapies....

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Publicado no:Mol Carcinog
Main Authors: Yamamoto, Tomomi M., McMellen, Alexandra, Watson, Zachary L., Aguilera, Jennifer, Ferguson, Rebecca, Nurmemmedov, Elmar, Thakar, Tanay, Moldovan, George-Lucian, Kim, Hyunmin, Cittelly, Diana M., Joglar, Annette M., Brennecke, Elyse P., Wilson, Heidi, Behbakht, Kian, Sikora, Matthew J., Bitler, Benjamin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537108/
https://ncbi.nlm.nih.gov/pubmed/31219654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23064
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