Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases

Here, we report a toxicity study, conducted on zebrafish larvae, of a series of coumarin and sulfamide compounds that were previously reported as inhibitors of human (h) metalloenzymes, carbonic anhydrases (CAs, EC 4.2.1.1). Due to the high relevance of hCA inhibitors as theragnostic agents, it is o...

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Publicat a:J Enzyme Inhib Med Chem
Autors principals: Aspatwar, Ashok, Berrino, Emanuela, Bua, Silvia, Carta, Fabrizio, Capasso, Clemente, Parkkila, Seppo, Supuran, Claudiu T.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
Brief Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534274/
https://ncbi.nlm.nih.gov/pubmed/32942905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1822829
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