Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors

The development of isoform selective inhibitors of the carbonic anhydrase (CA; EC 4.2.1.1) enzymes represents the key approach for the successful development of druggable small molecules. Herein we report a series of new benzenesulfamide derivatives (-NH-SO(2)NH(2)) bearing the 1-benzhydrylpiperazin...

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Vydáno v:Molecules
Hlavní autoři: Berrino, Emanuela, Bua, Silvia, Mori, Mattia, Botta, Maurizio, Murthy, Vallabhaneni S., Vijayakumar, Vijayaparthasarathi, Tamboli, Yasinalli, Bartolucci, Gianluca, Mugelli, Alessandro, Cerbai, Elisabetta, Supuran, Claudiu T., Carta, Fabrizio
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151984/
https://ncbi.nlm.nih.gov/pubmed/28672822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22071049
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