Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases

Here, we report a toxicity study, conducted on zebrafish larvae, of a series of coumarin and sulfamide compounds that were previously reported as inhibitors of human (h) metalloenzymes, carbonic anhydrases (CAs, EC 4.2.1.1). Due to the high relevance of hCA inhibitors as theragnostic agents, it is o...

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Bibliographic Details
Published in:J Enzyme Inhib Med Chem
Main Authors: Aspatwar, Ashok, Berrino, Emanuela, Bua, Silvia, Carta, Fabrizio, Capasso, Clemente, Parkkila, Seppo, Supuran, Claudiu T.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534274/
https://ncbi.nlm.nih.gov/pubmed/32942905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1822829
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