Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases

Here, we report a toxicity study, conducted on zebrafish larvae, of a series of coumarin and sulfamide compounds that were previously reported as inhibitors of human (h) metalloenzymes, carbonic anhydrases (CAs, EC 4.2.1.1). Due to the high relevance of hCA inhibitors as theragnostic agents, it is o...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Aspatwar, Ashok, Berrino, Emanuela, Bua, Silvia, Carta, Fabrizio, Capasso, Clemente, Parkkila, Seppo, Supuran, Claudiu T.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534274/
https://ncbi.nlm.nih.gov/pubmed/32942905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1822829
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