Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx)

The relationship between oxidative stress and cardiac stiffness is thought to involve modifications to the giant muscle protein titin, which in turn can determine the progression of heart disease. In vitro studies have shown that S-glutathionylation and disulfide bonding of titin fragments could alt...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Loescher, Christine M., Breitkreuz, Martin, Li, Yong, Nickel, Alexander, Unger, Andreas, Dietl, Alexander, Schmidt, Andreas, Mohamed, Belal A., Kötter, Sebastian, Schmitt, Joachim P., Krüger, Marcus, Krüger, Martina, Toischer, Karl, Maack, Christoph, Leichert, Lars I., Hamdani, Nazha, Linke, Wolfgang A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2020
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533878/
https://ncbi.nlm.nih.gov/pubmed/32929035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004900117
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