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Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection
Microglia are considered both pathogenic and protective during recovery from demyelination, but their precise role remains ill defined. Here, using an inhibitor of colony stimulating factor 1 receptor (CSF1R), PLX5622, and mice infected with a neurotropic coronavirus (mouse hepatitis virus [MHV], st...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7533697/ https://ncbi.nlm.nih.gov/pubmed/32929007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007814117 |
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