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General and robust covalently linked graphene oxide affinity grids for high-resolution cryo-EM

Affinity grids have great potential to facilitate rapid preparation of even quite impure samples in single-particle cryo-electron microscopy (EM). Yet despite the promising advances of affinity grids over the past decades, no single strategy has demonstrated general utility. Here we chemically funct...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Feng, Liu, Yanxin, Yu, Zanlin, Li, Sam, Feng, Shengjie, Cheng, Yifan, Agard, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533693/
https://ncbi.nlm.nih.gov/pubmed/32913054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009707117
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