Hair cell α9α10 nicotinic acetylcholine receptor functional expression regulated by ligand binding and deafness gene products

Auditory hair cells receive olivocochlear efferent innervation, which refines tonotopic mapping, improves sound discrimination, and mitigates acoustic trauma. The olivocochlear synapse involves α9α10 nicotinic acetylcholine receptors (nAChRs), which assemble in hair cells only coincident with cholin...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Gu, Shenyan, Knowland, Daniel, Matta, Jose A., O’Carroll, Min L., Davini, Weston B., Dhara, Madhurima, Kweon, Hae-Jin, Bredt, David S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533656/
https://ncbi.nlm.nih.gov/pubmed/32929005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013762117
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