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Treatment With Gemfibrozil Prevents the Progression of Chronic Kidney Disease in Obese Dahl Salt-Sensitive Rats

Recently, we reported that Dahl salt-sensitive leptin receptor mutant (SS(LepR)mutant) rats exhibit dyslipidemia and renal lipid accumulation independent of hyperglycemia that progresses to chronic kidney disease (CKD). Therefore, in the current study, we examined the effects of gemfibrozil, a lipid...

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Bibliografiske detaljer
Udgivet i:Front Physiol
Main Authors: Shields, Corbin A., Poudel, Bibek, McPherson, Kasi C., Brown, Andrea K., Ekperikpe, Ubong S., Browning, Evan, Sutton, Lamari, Cornelius, Denise C., Williams, Jan M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533555/
https://ncbi.nlm.nih.gov/pubmed/33071820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.566403
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