Treatment With Gemfibrozil Prevents the Progression of Chronic Kidney Disease in Obese Dahl Salt-Sensitive Rats

Recently, we reported that Dahl salt-sensitive leptin receptor mutant (SS(LepR)mutant) rats exhibit dyslipidemia and renal lipid accumulation independent of hyperglycemia that progresses to chronic kidney disease (CKD). Therefore, in the current study, we examined the effects of gemfibrozil, a lipid...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Shields, Corbin A., Poudel, Bibek, McPherson, Kasi C., Brown, Andrea K., Ekperikpe, Ubong S., Browning, Evan, Sutton, Lamari, Cornelius, Denise C., Williams, Jan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533555/
https://ncbi.nlm.nih.gov/pubmed/33071820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.566403
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