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Altered renal hemodynamics is associated with glomerular lipid accumulation in obese Dahl salt-sensitive leptin receptor mutant rats

The present study examined whether development of renal injury in the nondiabetic obese Dahl salt-sensitive leptin receptor mutant (SS(LepR)mutant) strain is associated with elevations in glomerular filtration rate and renal lipid accumulation. Baseline mean arterial pressure at 6 wk of age was simi...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: McPherson, Kasi C., Shields, Corbin A., Poudel, Bibek, Johnson, Ashley C., Taylor, Lateia, Stubbs, Cassandra, Nichols, Alyssa, Cornelius, Denise C., Garrett, Michael R., Williams, Jan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191445/
https://ncbi.nlm.nih.gov/pubmed/32068459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00438.2019
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