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Early development of podocyte injury independently of hyperglycemia and elevations in arterial pressure in nondiabetic obese Dahl SS leptin receptor mutant rats
The current study examined the effect of obesity on the development of renal injury within the genetic background of the Dahl salt-sensitive rat with a dysfunctional leptin receptor derived from zinc-finger nucleases (SS(LepR)mutant strain). At 6 wk of age, body weight was 35% higher in the SS(LepR)...
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| Publicat a: | Am J Physiol Renal Physiol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142236/ https://ncbi.nlm.nih.gov/pubmed/27465994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00590.2015 |
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