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Cyclin K interacts with β-catenin to induce Cyclin D1 expression and facilitates tumorigenesis and radioresistance in lung cancer

Rationale: Radioresistance remains the major cause of local relapse and distant metastasis in lung cancer. However, the underlying molecular mechanisms remain poorly defined. This study aimed to investigate the role and regulatory mechanism of Cyclin K in lung cancer radioresistance. Methods: Expres...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Yao, Guojun, Tang, Jing, Yang, Xijie, Zhao, Ye, Zhou, Rui, Meng, Rui, Zhang, Sheng, Dong, Xiaorong, Zhang, Tao, Yang, Kunyu, Wu, Gang, Xu, Shuangbing
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532664/
https://ncbi.nlm.nih.gov/pubmed/33042275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.42578
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