Pharmacological inhibition of mTORC1 increases CCKBR-specific tumor uptake of radiolabeled minigastrin analogue [(177)Lu]Lu-PP-F11N

Rationale: A high tumor-to-healthy-tissue uptake ratio of radiolabeled ligands is an essential prerequisite for safe and effective peptide receptor radionuclide therapy (PRRT). In the present study, we searched for novel opportunities to increase tumor-specific uptake of the radiolabeled minigastrin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Theranostics
Prif Awduron: Grzmil, Michal, Qin, Yun, Schleuniger, Carina, Frank, Stephan, Imobersteg, Stefan, Blanc, Alain, Spillmann, Martin, Berger, Philipp, Schibli, Roger, Behe, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ivyspring International Publisher 2020
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532663/
https://ncbi.nlm.nih.gov/pubmed/33042258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.45440
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