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Deep phylogeny of cancer drivers and compensatory mutations
Driver mutations (DM) are the genetic impetus for most cancers. The DM are assumed to be deleterious in species evolution, being eliminated by purifying selection unless compensated by other mutations. We present deep phylogenies for 84 cancer driver genes and investigate the prevalence of 434 DM ac...
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| Publié dans: | Commun Biol |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7532533/ https://ncbi.nlm.nih.gov/pubmed/33009502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01276-7 |
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