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Cancer-mutation network and the number and specificity of driver mutations

Cancer genomics has produced extensive information on cancer-associated genes, but the number and specificity of cancer-driver mutations remains a matter of debate. We constructed a bipartite network in which 7,665 tumors from 30 cancer types are connected via shared mutations in 198 previously iden...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Iranzo, Jaime, Martincorena, Iñigo, Koonin, Eugene V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042135/
https://ncbi.nlm.nih.gov/pubmed/29895694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803155115
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