Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex

The tripartite multidrug efflux system MexAB-OprM is a major actor in Pseudomonas aeruginosa antibiotic resistance by exporting a large variety of antimicrobial compounds. Crystal structures of MexB and of its Escherichia coli homolog AcrB had revealed asymmetric trimers depicting a directional drug...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Glavier, Marie, Puvanendran, Dhenesh, Salvador, Dimitri, Decossas, Marion, Phan, Gilles, Garnier, Cyril, Frezza, Elisa, Cece, Quentin, Schoehn, Guy, Picard, Martin, Taveau, Jean-Christophe, Daury, Laetitia, Broutin, Isabelle, Lambert, Olivier
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532149/
https://ncbi.nlm.nih.gov/pubmed/33009415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18770-5
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller