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The transcriptional elongation rate regulates alternative polyadenylation in yeast

Yeast cells undergoing the diauxic response show a striking upstream shift in poly(A) site utilization, with increased use of ORF-proximal poly(A) sites resulting in shorter 3’ mRNA isoforms for most genes. This altered poly(A) pattern is extremely similar to that observed in cells containing Pol II...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Geisberg, Joseph V, Moqtaderi, Zarmik, Struhl, Kevin
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532003/
https://ncbi.nlm.nih.gov/pubmed/32845240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59810
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