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An Adaptive Bayesian Design for Personalized Dosing in a Cancer Prevention Trial
INTRODUCTION: In biomarker-driven clinical trials, translational strategies typically involve moving findings from animal experiments to human trials. Typically, the translation is static, using a fixed model derived from animal experiments for the duration of the trial. But Bayesian designs, capabl...
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| Publicat a: | Am J Prev Med |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7531353/ https://ncbi.nlm.nih.gov/pubmed/32951684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amepre.2020.04.023 |
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