Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos

[Image: see text] Many reagents have emerged to study the function of specific enzymes in vitro. On the other hand, target specific reagents are scarce or need improvement, allowing investigations of the function of individual enzymes in their native cellular context. Here we report the development...

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Опубликовано в: :J Am Chem Soc
Главные авторы: Kooij, Raymond, Liu, Sijia, Sapmaz, Aysegul, Xin, Bo-Tao, Janssen, George M. C., van Veelen, Peter A., Ovaa, Huib, Dijke, Peter ten, Geurink, Paul P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2020
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530896/
https://ncbi.nlm.nih.gov/pubmed/32886496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c07726
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