Circadian Rhythm Protein Bmal1 Modulates Cartilage Gene Expression in Temporomandibular Joint Osteoarthritis via the MAPK/ERK Pathway

The purpose of this study was to elucidate the role of the circadian gene Bmal1 in human cartilage and its crosstalk with the MAPK/ERK signaling pathway in temporomandibular joint osteoarthritis (TMJ-OA). We verified the periodical variation of the circadian gene Bmal1 and then established a modifie...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Chen, Guokun, Zhao, Haoming, Ma, Shixing, Chen, Lei, Wu, Gaoyi, Zhu, Yong, Zhu, Jie, Ma, Chuan, Zhao, Huaqiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530270/
https://ncbi.nlm.nih.gov/pubmed/33041790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.527744
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