Circadian Rhythm Protein Bmal1 Modulates Cartilage Gene Expression in Temporomandibular Joint Osteoarthritis via the MAPK/ERK Pathway

The purpose of this study was to elucidate the role of the circadian gene Bmal1 in human cartilage and its crosstalk with the MAPK/ERK signaling pathway in temporomandibular joint osteoarthritis (TMJ-OA). We verified the periodical variation of the circadian gene Bmal1 and then established a modifie...

詳細記述

保存先:
書誌詳細
出版年:Front Pharmacol
主要な著者: Chen, Guokun, Zhao, Haoming, Ma, Shixing, Chen, Lei, Wu, Gaoyi, Zhu, Yong, Zhu, Jie, Ma, Chuan, Zhao, Huaqiang
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
Pharmacology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530270/
https://ncbi.nlm.nih.gov/pubmed/33041790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.527744
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