Arming HSV-Based Oncolytic Viruses with the Ability to Redirect the Host’s Innate Antiviral Immunity to Attack Tumor Cells

One of the major hurdles for cancer immunotherapy is the host’s innate antiviral defense mechanisms. They include innate immune cells, such as natural killer (NK) cells and macrophages, which can be recruited within hours to the site of injection to clear the introduced oncolytic viruses. Here, we r...

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Bibliographic Details
Published in:Mol Ther Oncolytics
Main Authors: Fu, Xinping, Tao, Lihua, Wu, Wanfu, Zhang, Xiaoliu
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530262/
https://ncbi.nlm.nih.gov/pubmed/33024817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.09.002
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