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Arming HSV-Based Oncolytic Viruses with the Ability to Redirect the Host’s Innate Antiviral Immunity to Attack Tumor Cells

One of the major hurdles for cancer immunotherapy is the host’s innate antiviral defense mechanisms. They include innate immune cells, such as natural killer (NK) cells and macrophages, which can be recruited within hours to the site of injection to clear the introduced oncolytic viruses. Here, we r...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Fu, Xinping, Tao, Lihua, Wu, Wanfu, Zhang, Xiaoliu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530262/
https://ncbi.nlm.nih.gov/pubmed/33024817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.09.002
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