Comparison of infectivity and spread between HSV-1 and HSV-2 based oncolytic viruses on tumor cells with different receptor expression profiles

Herpes simplex virus (HSV) is one of the many viruses that have been modified or adapted for oncolytic purposes. There are two serotypes of HSV, HSV-1 and HSV-2. The majority of oncolytic HSVs, including T-VEC which has recently been approved by the US Food and Drug Administration (FDA) for clinical...

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Foilsithe in:Oncotarget
Main Authors: Fu, Xinping, Tao, Lihua, Wang, Pin-Yi, Cripe, Timothy P., Zhang, Xiaoliu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2018
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940406/
https://ncbi.nlm.nih.gov/pubmed/29765544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25096
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