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Comparison of infectivity and spread between HSV-1 and HSV-2 based oncolytic viruses on tumor cells with different receptor expression profiles

Herpes simplex virus (HSV) is one of the many viruses that have been modified or adapted for oncolytic purposes. There are two serotypes of HSV, HSV-1 and HSV-2. The majority of oncolytic HSVs, including T-VEC which has recently been approved by the US Food and Drug Administration (FDA) for clinical...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fu, Xinping, Tao, Lihua, Wang, Pin-Yi, Cripe, Timothy P., Zhang, Xiaoliu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940406/
https://ncbi.nlm.nih.gov/pubmed/29765544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25096
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