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Comparison of infectivity and spread between HSV-1 and HSV-2 based oncolytic viruses on tumor cells with different receptor expression profiles

Herpes simplex virus (HSV) is one of the many viruses that have been modified or adapted for oncolytic purposes. There are two serotypes of HSV, HSV-1 and HSV-2. The majority of oncolytic HSVs, including T-VEC which has recently been approved by the US Food and Drug Administration (FDA) for clinical...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Fu, Xinping, Tao, Lihua, Wang, Pin-Yi, Cripe, Timothy P., Zhang, Xiaoliu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940406/
https://ncbi.nlm.nih.gov/pubmed/29765544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25096
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