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Enhancing venetoclax activity in hematological malignancies

INTRODUCTION: Targeting anti-apoptotic pathways involving the BCL2 family proteins represents a novel treatment strategy in hematologic malignancies. Venetoclax, a selective BCL2 inhibitor, represents the first approved agent of this class, and is currently used in CLL and AML. However, monotherapy...

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Detalhes bibliográficos
Publicado no:Expert Opin Investig Drugs
Main Authors: Satta, Toshihisa, Grant, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529910/
https://ncbi.nlm.nih.gov/pubmed/32600066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13543784.2020.1789588
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