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In vivo antitumor activity by dual stromal and tumor-targeted oncolytic measles viruses

The tumor stroma acts as a barrier that limits the efficacy of systemically administered oncolytic viruses (OV). We previously demonstrated that stromal-selective, retargeted oncolytic measles viruses (MVs) delay in vivo tumor progression. To further characterize the contribution of stromal targetin...

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Detalhes bibliográficos
Publicado no:Cancer Gene Ther
Main Authors: Jing, Yuqi, Chavez, Valery, Khatwani, Natasha, Ban, Yuguang, Espejo, Andrea P., Chen, Xi, Merchan, Jaime R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529863/
https://ncbi.nlm.nih.gov/pubmed/32231231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41417-020-0171-1
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