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Molecular Effects of Stromal Selective Targeting by uPAR Retargeted Oncolytic Virus in Breast Cancer

The tumor microenvironment (TME) is a relevant target for novel biological therapies. MV-m-uPA and MV-h-uPA are fully retargeted, species-specific, oncolytic measles viruses (MVs) directed against murine or human urokinase receptor (PLAUR/uPAR), expressed in tumor and stromal cells. The effects of s...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Jing, Yuqi, Chavez, Valery, Ban, Yuguang, Acquavella, Nicolas, El-Ashry, Doraya, Pronin, Alexey, Chen, Xi, Merchan, Jaime R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682105/
https://ncbi.nlm.nih.gov/pubmed/28679779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0016
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