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SPRY1 promotes the degradation of uPAR and inhibits uPAR-mediated cell adhesion and proliferation

Urokinase plasminogen activator receptor (uPAR) is a GPI anchored cell surface protein that is closely associated with invasion, migration, and metastasis of cancer cells. Many functional extracellular proteins and transmembrane receptors interact with uPAR. However, few studies have examined the as...

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Liu, Xiufeng, Lan, Yan, Zhang, Di, Wang, Kai, Wang, Yao, Hua, Zi-Chun
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266704/
https://ncbi.nlm.nih.gov/pubmed/25520860
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