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In vivo antimetastatic effects of uPAR retargeted measles virus in syngeneic and xenograft models of mammary cancer

PURPOSE: The urokinase receptor (uPAR) plays a critical role in breast cancer (BC) progression and metastases, and is a validated target for novel therapies. The current study investigates the effects of MV-uPA, an oncolytic measles virus fully retargeted against uPAR in syngeneic and xenograft BC m...

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Vydáno v:Breast Cancer Res Treat
Hlavní autoři: Jing, Yuqi, Bejarano, Marcela Toro, Zaias, Julia, Merchan, Jaime R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302411/
https://ncbi.nlm.nih.gov/pubmed/25519042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-3236-8
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