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Phosphodiesterase isoforms and cAMP compartments in the development of new therapies for obstructive pulmonary diseases

The second messenger molecule 3’5’-cyclic adenosine monophosphate (cAMP) imparts several beneficial effects in lung diseases such as asthma, chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). While cAMP is bronchodilatory in asthma and COPD, it also displays anti-f...

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Bibliographic Details
Published in:Curr Opin Pharmacol
Main Authors: Schmidt, Martina, Cattani-Cavalieri, Isabella, Nuñez, Francisco J, Ostrom, Rennolds S
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529846/
https://ncbi.nlm.nih.gov/pubmed/32622335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2020.05.002
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