Metal ions shape α-synuclein

α-Synuclein is an intrinsically disordered protein that can self-aggregate and plays a major role in Parkinson’s disease (PD). Elevated levels of certain metal ions are found in protein aggregates in neurons of people suffering from PD, and environmental exposure has also been linked with neurodegen...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Moons, Rani, Konijnenberg, Albert, Mensch, Carl, Van Elzen, Roos, Johannessen, Christian, Maudsley, Stuart, Lambeir, Anne-Marie, Sobott, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529799/
https://ncbi.nlm.nih.gov/pubmed/33004902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73207-9
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