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Metal ions shape α-synuclein

α-Synuclein is an intrinsically disordered protein that can self-aggregate and plays a major role in Parkinson’s disease (PD). Elevated levels of certain metal ions are found in protein aggregates in neurons of people suffering from PD, and environmental exposure has also been linked with neurodegen...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Moons, Rani, Konijnenberg, Albert, Mensch, Carl, Van Elzen, Roos, Johannessen, Christian, Maudsley, Stuart, Lambeir, Anne-Marie, Sobott, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529799/
https://ncbi.nlm.nih.gov/pubmed/33004902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73207-9
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