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Calpain Inhibition Decreases Myocardial Fibrosis in Chronically Ischemic Hypercholesterolemic Swine
OBJECTIVES: Calpain activation during ischemia is known to play critical roles in myocardial remodeling. We hypothesize that calpain inhibition (CI) may serve to reverse and/or prevent fibrosis in chronically ischemic myocardium. METHODS: Yorkshire swine were fed a high cholesterol diet for 4 weeks...
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| Publicado no: | J Thorac Cardiovasc Surg |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7529741/ https://ncbi.nlm.nih.gov/pubmed/32359903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2019.11.150 |
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